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- 抗原 See all Emerin (EMD) 抗体
- Emerin (EMD)
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抗原表位
- AA 1-48
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Emerin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity purified
- 免疫原
- Amino acids 1-48 (MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRL-human) were used as the immunogen for the Emerin antibody.
- 亚型
- IgG
- Top Product
- Discover our top product EMD Primary Antibody
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anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal EMD-2168 unconjugated
anti-Emerin (EMD) (AA 56-167) antibodyEMD 适用: 人 WB, IF, IHC, StM 宿主: 小鼠 Monoclonal EMD-2167 unconjugated
anti-Emerin (EMD) (AA 1-222) antibodyEMD 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8F5A8 unconjugated
anti-Emerin (EMD) (AA 1-222) antibodyEMD 适用: 人 WB, ELISA, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Emerin (EMD) (AA 1-110) antibodyEMD 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B9 unconjugated
anti-Emerin (EMD) (AA 1-254) antibodyEMD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Emerin (EMD) antibodyEMD 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Emerin (EMD) (AA 1-188) antibodyEMD 适用: 人, 兔 WB, IF, ICC 宿主: 小鼠 Monoclonal MANEM1(5D10) unconjugated
anti-Emerin (EMD) (AA 114-183) antibodyEMD 适用: 小鼠, 大鼠, Hamster WB, IF, ICC, EM 宿主: 绵羊 Polyclonal unconjugated
anti-Emerin (EMD) antibodyEMD 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL0201 unconjugated
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- 应用备注
- Optimal dilution of the Emerin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Emerin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- 抗原
- Emerin (EMD)
- 别名
- Emerin (EMD 产品)
- 别名
- fj58f01 antibody, wu:fj58f01 antibody, EMD antibody, Bocks antibody, Bocksbeutel antibody, CG9424 antibody, Dmel\\CG9424 antibody, emerin antibody, emd antibody, xemd1 antibody, xemerin2 antibody, xemd2 antibody, xemerin1 antibody, EDMD antibody, LEMD5 antibody, STA antibody, AW550900 antibody, Sta antibody, emerin antibody, emerin (Emery-Dreifuss muscular dystrophy) antibody, bocksbeutel antibody, emerin L homeolog antibody, emerin S homeolog antibody, EMD antibody, emd antibody, bocks antibody, emd.L antibody, emd.S antibody, Emd antibody
- 背景
- Emerin is a serine-rich nuclear membrane protein that in humans is encoded by the EMD gene. And this gene is mapped to Xq28. Emerin is a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Emery-Dreifuss muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the EMD (also known clinically as STA) gene. Emerin appears to be involved in mechanotransduction, as emerin-deficient mouse fibroblasts failed to transduce normal mechanosensitive gene expression responses to strain stimuli. In cardiac muscle, emerin is also found complexed to beta-catenin at adherens junctions of intercalated discs, and cardiomyocytes from hearts lacking emerin showed beta-catenin redistribution as well as perturbed intercalated disc architecture and myocyte shape. This interaction appears to be regulated by glycogen synthase kinase 3 beta.
- UniProt
- P50402
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