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Emerin 抗体 (AA 1-48)

This anti-Emerin antibody is a 兔多克隆 antibody detecting Emerin in WB 和 IHC (p). Suitable for 人, 小鼠和大鼠.

Western blot testing of 1) rat skeletal muscle, 2) mouse heart and 3) human HeLa lysate with Emerin antibody at 0. (Emerin 抗体 (AA 1-48))

IHC testing of FFPE human lung cancer tissue with Emerin antibody at 1ug/ml. (Emerin 抗体 (AA 1-48))

2 images

产品编号 ABIN5647115

发货至: 中国

Quick Overview for Emerin 抗体 (AA 1-48) (ABIN5647115)

抗原

See all Emerin (EMD) 抗体

Emerin (EMD)

适用

82
16
13
3
2
1
1
1
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

41
5
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This Emerin antibody is un-conjugated

应用范围

70
34
28
20
16
13
13
8
7
7
6
3
2
2
2
2
1
1

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product EMD Primary Antibody

抗原表位
24

15

9

8

3

3

2

2

1

1

1

1

1

1

1

1
AA 1-48

纯化方法

Antigen affinity purified

免疫原

Amino acids 1-48 (MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRL-human) were used as the immunogen for the Emerin antibody.

亚型

IgG
anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal EMD-2168 unconjugated

anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal EMD-2167 unconjugated

anti-Emerin (EMD) (AA 1-222) antibody
EMD 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8F5A8 unconjugated

anti-Emerin (EMD) (AA 1-222) antibody
EMD 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Emerin (EMD) (AA 1-110) antibody
EMD 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B9 unconjugated

anti-Emerin (EMD) (AA 1-254) antibody
EMD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Emerin (EMD) (AA 1-220) antibody
EMD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Emerin (EMD) antibody
EMD 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Emerin (EMD) (AA 1-188) antibody
EMD 适用: 人, 兔 WB, IF, ICC 宿主: 小鼠 Monoclonal MANEM1(5D10) unconjugated

anti-Emerin (EMD) (AA 114-183) antibody
EMD 适用: 小鼠, 大鼠, Hamster WB, IF, ICC, EM 宿主: 绵羊 Polyclonal unconjugated

应用备注

Optimal dilution of the Emerin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Emerin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Emerin (EMD)

别名

Emerin

背景

Emerin is a serine-rich nuclear membrane protein that in humans is encoded by the EMD gene. And this gene is mapped to Xq28. Emerin is a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Emery-Dreifuss muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the EMD (also known clinically as STA) gene. Emerin appears to be involved in mechanotransduction, as emerin-deficient mouse fibroblasts failed to transduce normal mechanosensitive gene expression responses to strain stimuli. In cardiac muscle, emerin is also found complexed to beta-catenin at adherens junctions of intercalated discs, and cardiomyocytes from hearts lacking emerin showed beta-catenin redistribution as well as perturbed intercalated disc architecture and myocyte shape. This interaction appears to be regulated by glycogen synthase kinase 3 beta.

UniProt

P50402

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