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Emerin 抗体 (AA 1-48)

The 兔多克隆 anti-Emerin antibody (ABIN5647115) specifically detects Emerin in WB 和 IHC (p). The antibody is reactive with 人, 小鼠和大鼠 samples.

Western blot testing of 1) rat skeletal muscle, 2) mouse heart and 3) human HeLa lysate with Emerin antibody at 0. (Emerin 抗体 (AA 1-48))

IHC testing of FFPE human lung cancer tissue with Emerin antibody at 1ug/ml. (Emerin 抗体 (AA 1-48))

2 images

产品编号 ABIN5647115

发货至: 中国

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Quick Overview for Emerin 抗体 (AA 1-48) (ABIN5647115)

抗原

See all Emerin (EMD) 抗体

Emerin (EMD)

适用

89
26
23
3
2
1
1
1
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

41
6
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

This Emerin antibody is un-conjugated

应用范围

78
41
35
18
17
15
13
13
8
7
6
3
2
2
2
2
1
1

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product EMD Primary Antibody

抗原表位
22

15

8

7

3

2

2

2

1

1

1

1

1

1

1

1
AA 1-48

纯化方法

Antigen affinity purified

免疫原

Amino acids 1-48 (MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRL-human) were used as the immunogen for the Emerin antibody.

亚型

IgG
anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, IF, StM 宿主: 小鼠 Monoclonal EMD-2167 unconjugated

anti-Emerin (EMD) (AA 56-167) antibody
EMD 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal EMD-2168 unconjugated

anti-Emerin (EMD) (AA 1-222) antibody
EMD 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8F5A8 unconjugated

anti-Emerin (EMD) (AA 1-222) antibody
EMD 适用: 人 WB, IHC, IF, ELISA, IP 宿主: 兔 Polyclonal unconjugated

anti-Emerin (EMD) antibody
KD Validated EMD 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5320 unconjugated Recombinant Antibody

anti-Emerin (EMD) (AA 1-110) antibody
EMD 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B9 unconjugated

anti-Emerin (EMD) (AA 1-220) antibody
EMD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Emerin (EMD) antibody
EMD 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Emerin (EMD) (AA 1-254) antibody
EMD 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Emerin (EMD) (AA 1-188) antibody
EMD 适用: 人, 兔 WB, IF, ICC 宿主: 小鼠 Monoclonal MANEM1(5D10) unconjugated

应用备注

Optimal dilution of the Emerin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the Emerin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

Emerin (EMD)

别名

Emerin

背景

Emerin is a serine-rich nuclear membrane protein that in humans is encoded by the EMD gene. And this gene is mapped to Xq28. Emerin is a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Emery-Dreifuss muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the EMD (also known clinically as STA) gene. Emerin appears to be involved in mechanotransduction, as emerin-deficient mouse fibroblasts failed to transduce normal mechanosensitive gene expression responses to strain stimuli. In cardiac muscle, emerin is also found complexed to beta-catenin at adherens junctions of intercalated discs, and cardiomyocytes from hearts lacking emerin showed beta-catenin redistribution as well as perturbed intercalated disc architecture and myocyte shape. This interaction appears to be regulated by glycogen synthase kinase 3 beta.

UniProt

P50402

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