alpha Defensin 1 抗体 (AA 65-94)
Quick Overview for alpha Defensin 1 抗体 (AA 65-94) (ABIN5647108)
抗原
See all alpha Defensin 1 (DEFA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-94
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids 65-94 (ACYCRIPACIAGERRYGTCIYQGRLWAFCC) from the human protein were used as the immunogen for the Alpha Defensin 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Alpha Defensin 1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Alpha Defensin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
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别名
- Alpha Defensin 1 / DEFA1
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背景
- Defensin, alpha 1, also known as human alpha defensin 1, human neutrophil peptide 1 (HNP-1) or neutrophil defensin 1 is a human protein that is encoded by the DEFA1 gene. Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
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UniProt
- P59665
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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