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AIRE 抗体

This anti-AIRE antibody is a 兔 多克隆 antibody detecting AIRE in WB 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN5647007
发货至: 中国

Quick Overview for AIRE 抗体 (ABIN5647007)

抗原

See all AIRE 抗体
AIRE (Autoimmune Regulator (AIRE))

适用

  • 54
  • 26
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
人, 大鼠

宿主

  • 50
  • 7
  • 1
  • 1

克隆类型

  • 57
  • 1
多克隆

标记

  • 43
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This AIRE antibody is un-conjugated

应用范围

  • 44
  • 27
  • 20
  • 14
  • 12
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • 纯化方法

    Antigen affinity purified

    免疫原

    Amino acids M1-K120 from the human protein were used as the immunogen for the AIRE antibody.

    亚型

    IgG
  • 应用备注

    Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution, store at 4°C. After reconstitution, the AIRE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    AIRE (Autoimmune Regulator (AIRE))

    别名

    AIRE

    背景

    The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

    UniProt

    O43918

    途径

    Chromatin Binding
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