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G3BP1 抗体 (AA 214-303)

Cited in 4+ publications. This 小鼠 单克隆 anti-G3BP1 antibody (Clone 2F3) specifically detects G3BP1 in WB, IF, ELISA, IHC (p) 和 RNAi. The antibody is reactive with 人 samples.
产品编号 ABIN564390
发货至: 中国
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Quick Overview for G3BP1 抗体 (AA 214-303) (ABIN564390)

抗原

See all G3BP1 抗体
G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

适用

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宿主

  • 97
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小鼠

克隆类型

  • 75
  • 29
单克隆

标记

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This G3BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

2F3
  • 抗原表位

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    AA 214-303

    原理

    Mouse monoclonal antibody raised against a partial recombinant G3BP.

    序列

    KPEPVLEETA PEDAQKSSSP APADIAQTVQ EDLRTFSWAS VTSKNLPPSG AVPVTGIPPH VVKVPASQPR PESKPESQIP PQRPQRDQRV

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    G3BP (AAH06997, 214 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: "Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum." in: Journal of neurochemistry, Vol. 139, Issue 3, pp. 349-368, (2016) (PubMed).

    Kaehler, Isensee, Hucho, Lehrach, Krobitsch: "5-Fluorouracil affects assembly of stress granules based on RNA incorporation." in: Nucleic acids research, Vol. 42, Issue 10, pp. 6436-47, (2014) (PubMed).

    Martin, Zekri, Metz, Maurice, Chebli, Vignes, Tazi: "Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons." in: Journal of neurochemistry, (2013) (PubMed).

    Norazit, Meedeniya, Nguyen, Mackay-Sim: "Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle." in: Brain research, Vol. 1360, pp. 119-29, (2010) (PubMed).

  • 抗原

    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

    别名

    G3BP1

    背景

    Full Gene Name: GTPase activating protein (SH3 domain) binding protein 1
    Synonyms: G3BP,HDH-VIII,MGC111040

    基因ID

    10146

    途径

    SARS-CoV-2 Protein Interactome
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