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USP15 抗体 (AA 1-235)

USP15 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C10 unconjugated
产品编号 ABIN564282
发货至: 中国
  • 抗原 See all USP15 抗体
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    抗原表位
    • 9
    • 8
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-235
    适用
    • 48
    • 27
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 47
    • 1
    小鼠
    克隆类型
    • 47
    单克隆
    标记
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This USP15 antibody is un-conjugated
    应用范围
    • 36
    • 27
    • 9
    • 8
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    Mouse monoclonal antibody raised against a full length recombinant USP15.
    序列
    MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ GMFVKHCKVE VYLTELKLCE NGNMNNVVTR RFSKADTIDT IEKEIRKIFS IPDEKETRLW NKYMSNTFEP LNKPDSTIQD AGLYQGQVLV IEQKNEDGTW PRGPSTPKKP LEQSC
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    USP15 (AAH20688, 1 a.a. ~ 235 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1C10
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Pauli, Chan, Davis, Gableske, Wang, Feister, Gack: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." in: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).

    García-Caballero, Gadotti, Stemkowski, Weiss, Souza, Hodgkinson, Bladen, Chen, Hamid, Pizzoccaro, Deage, François, Bourinet, Zamponi: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).

    Cornelissen, Haddad, Wauters, Van Humbeeck, Mandemakers, Koentjoro, Sue, Gevaert, De Strooper, Verstreken, Vandenberghe: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." in: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).

    Fernandez-Sanchez, Sechet, Margottin-Goguet, Rogge, Bianchi: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).

    Vos, Altreuter, White, Howley: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).

    Xu, Takanashi, Oikawa, Tanaka, Nishi, Isaka, Kudo, Kuroda: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." in: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).

    Cayli, Klug, Chapiro, Fröhlich, Krasteva, Orel, Meinhardt: "COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34944-53, (2009) (PubMed).

    Miyauchi, Kato, Tokunaga, Iwai: "The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination." in: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16622-31, (2008) (PubMed).

    Schweitzer, Bozko, Dubiel, Naumann: "CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha." in: The EMBO journal, Vol. 26, Issue 6, pp. 1532-41, (2007) (PubMed).

  • 抗原
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    别名
    USP15 (USP15 产品)
    别名
    USP15 antibody, UNP antibody, UNPH-2 antibody, UNPH4 antibody, 4921514G19Rik antibody, AI327321 antibody, E430033I05Rik antibody, Gcap18 antibody, mKIAA0529 antibody, Ubp109 antibody, ubiquitin specific peptidase 15 antibody, universal stress protein UspA antibody, ubiquitin carboxyl-terminal hydrolase 15 antibody, USP15 antibody, RR_RS05795 antibody, LOC100090554 antibody, usp15 antibody, Usp15 antibody
    背景
    Full Gene Name: ubiquitin specific peptidase 15
    Synonyms: KIAA0529,MGC131982,MGC149838,MGC74854,UNPH4
    基因ID
    9958
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