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OXSR1 抗体 (AA 351-450)

Cited in 5+ publications. This anti-OXSR1 antibody is a 小鼠 单克隆 antibody detecting OXSR1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN564274
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for OXSR1 抗体 (AA 351-450) (ABIN564274)

抗原

See all OXSR1 抗体
OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

适用

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宿主

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小鼠

克隆类型

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  • 9
单克隆

标记

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This OXSR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

5D5
  • 抗原表位

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    AA 351-450

    原理

    Mouse monoclonal antibody raised against a partial recombinant OXSR1.

    序列

    KAAISQLRSP RVKESISNSE LFPTTDPVGT LLQVPEQISA HLPQPAGQIA TQPTQVSLPP TAEPAKTAQA LSSGSGSQET KIPISLVLRL RNSKKELNDI

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    OXSR1 (AAH08726.1, 351 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Wakabayashi, Mori, Isobe, Sohara, Susa, Araki, Chiga, Kikuchi, Nomura, Mori, Matsuo, Murata, Nomura, Asano, Kawaguchi, Nonoyama, Rai, Sasaki, Uchida: "Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension." in: Cell reports, Vol. 3, Issue 3, pp. 858-68, (2013) (PubMed).

    Trudu, Janas, Lanzani, Debaix, Schaeffer, Ikehata, Citterio, Demaretz, Trevisani, Ristagno, Glaudemans, Laghmani, DellAntonio, Loffing, Rastaldi, Manunta, Devuyst, Rampoldi: "Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression." in: Nature medicine, Vol. 19, Issue 12, pp. 1655-60, (2013) (PubMed).

    Susa, Kita, Iwamoto, Yang, Lin, Ohta, Sohara, Rai, Sasaki, Alessi, Uchida: "Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels." in: Clinical and experimental nephrology, Vol. 16, Issue 4, pp. 530-8, (2012) (PubMed).

    Susa, Sohara, Isobe, Chiga, Rai, Sasaki, Uchida: "WNK-OSR1/SPAK-NCC signal cascade has circadian rhythm dependent on aldosterone." in: Biochemical and biophysical research communications, Vol. 427, Issue 4, pp. 743-7, (2012) (PubMed).

    Chiga, Rafiqi, Alessi, Sohara, Ohta, Rai, Sasaki, Uchida: "Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade." in: Journal of cell science, Vol. 124, Issue Pt 9, pp. 1391-5, (2011) (PubMed).

  • 抗原

    OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

    别名

    OXSR1

    背景

    Full Gene Name: oxidative-stress responsive 1
    Synonyms: KIAA1101,OSR1

    基因ID

    9943

    途径

    Tube Formation
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