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MFN2 抗体 (AA 661-757)

Name: MFN2 抗体 (AA 661-757)
SKU: ABIN564263
Availability: OutOfStock

There are 8+ publications for this product available. The 小鼠单克隆 anti-MFN2 antibody is suitable to detect MFN2 in samples from 人. It has been validated for WB, ELISA, IHC (p) 和 RNAi.

MFN2 monoclonal antibody (M03), clone 4H8 Western Blot analysis of MFN2 expression in HeLa . (MFN2 抗体 (AA 661-757))

Immunoperoxidase of monoclonal antibody to MFN2 on formalin-fixed paraffin-embedded human heart. (MFN2 抗体 (AA 661-757))

ISt

Western blot analysis of MFN2 over-expressed 293 cell line, cotransfected with MFN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (MFN2 抗体 (AA 661-757))

Detection limit for recombinant GST tagged MFN2 is approximately 1ng/ml as a capture antibody. (MFN2 抗体 (AA 661-757))

ELISA

Western Blot analysis of MFN2 expression in transfected 293T cell line by MFN2 monoclonal antibody (M03), clone 4H8. (MFN2 抗体 (AA 661-757))

MFN2 monoclonal antibody (M03), clone 4H8. (MFN2 抗体 (AA 661-757))

Western Blot detection against Immunogen (36. (MFN2 抗体 (AA 661-757))

7 images

(8 references)

产品编号 ABIN564263

发货至: 中国

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Quick Overview for MFN2 抗体 (AA 661-757) (ABIN564263)

抗原

See all MFN2 抗体

MFN2 (Mitofusin 2 (MFN2))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This MFN2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

克隆位点

4H8

抗原表位
24

11

7

6

6

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 661-757

原理

Mouse monoclonal antibody raised against a partial recombinant MFN2.

序列

FKRQFVEHAS EKLQLVISYT GSNCSHQVQQ ELSGTFAHLC QQVDVTRENL EQEIAAMNKK IEVLDSLQSK AKLLRNKAGW LDSELNMFTH QYLQPSR

交叉反应

人, 大鼠

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

MFN2 (NP_055689, 661 a.a. ~ 757 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG2a
anti-Mitofusin 2 (MFN2) (AA 1-120) antibody
MFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 500-600) antibody
MFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 687-757) antibody
MFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 447-476) antibody
MFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (N-Term) antibody
MFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 unconjugated

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 HRP

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Biotin

anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (PE)
MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 PE

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

Esteves, G-Fernandes, Santos, Januário, Cardoso: "The Upshot of LRRK2 Inhibition to Parkinson's Disease Paradigm." in: Molecular neurobiology, (2015) (PubMed).

Fiuza-Luces, Delmiro, Soares-Miranda, González-Murillo, Martínez-Palacios, Ramírez, Lucia, Morán: "Exercise training can induce cardiac autophagy at end-stage chronic conditions: insights from a graft-versus-host-disease mouse model." in: Brain, behavior, and immunity, Vol. 39, pp. 56-60, (2014) (PubMed).

Lally, Herbst, Matravadia, Maher, Perry, Ventura-Clapier, Holloway: "Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics." in: PLoS ONE, Vol. 8, Issue 1, pp. e55660, (2013) (PubMed).

Russell, Lamon, Boon, Wada, Güller, Brown, Chibalin, Zierath, Snow, Stepto, Wadley, Akimoto: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, (2013) (PubMed).

Cosson, Marchetti, Ravazzola, Orci: "Mitofusin-2 independent juxtaposition of endoplasmic reticulum and mitochondria: an ultrastructural study." in: PLoS ONE, Vol. 7, Issue 9, pp. e46293, (2012) (PubMed).

Morán, Rivera, Sánchez-Aragó, Blázquez, Merinero, Ugalde, Arenas, Cuezva, Martín: "Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts." in: Biochimica et biophysica acta, Vol. 1802, Issue 5, pp. 443-53, (2010) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
抗原

MFN2 (Mitofusin 2 (MFN2))

别名

MFN2

背景

Full Gene Name: mitofusin 2
Synonyms: CMT2A,CMT2A2,CPRP1,HSG,KIAA0214,MARF

基因ID

9927

NCBI登录号

NM_014874

途径

Skeletal Muscle Fiber Development