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USP9X 抗体 (AA 1-90)

Cited in 6+ publications. This anti-USP9X antibody is a 小鼠 单克隆 antibody detecting USP9X in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN563570
发货至: 中国
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Quick Overview for USP9X 抗体 (AA 1-90) (ABIN563570)

抗原

See all USP9X 抗体
USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

适用

  • 66
  • 44
  • 40
  • 6
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  • 4
  • 2
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  • 1
  • 1

宿主

  • 60
  • 4
  • 2
小鼠

克隆类型

  • 43
  • 23
单克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
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This USP9X antibody is un-conjugated

应用范围

  • 45
  • 20
  • 16
  • 13
  • 13
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  • 9
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  • 6
Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

1C4
  • 抗原表位

    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-90

    原理

    Mouse monoclonal antibody raised against a partial recombinant USP9X.

    序列

    MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    USP9X (NP_068706, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kim, Kim, Park, Lee, Lim: "Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition." in: EMBO reports, Vol. 17, Issue 1, pp. 64-78, (2016) (PubMed).

    Wolfsperger, Hogh-Binder, Schittenhelm, Psaras, Ritter, Bornes, Huber, Jendrossek, Rudner: "Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms." in: Cell death & disease, Vol. 7, pp. e2039, (2016) (PubMed).

    Wang, Xie, Li, Owonikoko, Ramalingam, Khuri, Curran, Wang, Deng: "Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis." in: Cell death and differentiation, Vol. 21, Issue 7, pp. 1160-9, (2014) (PubMed).

    Mazumder, Choudhary, Al-Harbi, Almasan: "Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells." in: Cancer research, Vol. 72, Issue 12, pp. 3069-79, (2012) (PubMed).

    Trivigno, Essmann, Huber, Rudner: "Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1." in: Neoplasia (New York, N.Y.), Vol. 14, Issue 10, pp. 893-904, (2012) (PubMed).

    Hikita, Takehara, Shimizu, Kodama, Shigekawa, Iwase, Hosui, Miyagi, Tatsumi, Ishida, Li, Kanto, Hiramatsu, Hayashi: "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1310-21, (2010) (PubMed).

  • 抗原

    USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

    别名

    USP9X

    背景

    Full Gene Name: ubiquitin specific peptidase 9, X-linked
    Synonyms: DFFRX,FAF,FAM

    基因ID

    8239

    NCBI登录号

    NM_021906
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