R-RAS2 抗体 (PE)
This anti- antibody is a 小鼠 单克隆 antibody detecting in ICFC. Suitable for 人.
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Quick Overview for R-RAS2 抗体 (PE) (ABIN5633276)
抗原
R-RAS2
适用
人
宿主
小鼠
克隆类型
单克隆
标记
PE
应用范围
Intracellular Flow Cytometry (ICFC)
克隆位点
EM-50
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原理
- Anti-R-RAS2 PE
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特异性
- The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human TC21
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亚型
- IgG1 kappa
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anti-R-RAS2 antibody
适用: 人 ELISA, FACS, ICC, WB 宿主: 小鼠 Monoclonal EM-50 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- R-RAS2
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背景
- RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2
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基因ID
- 22800
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UniProt
- P62070
抗原
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