R-RAS2 抗体 (PE)
The PE-conjugated 小鼠 单克隆 anti-R-RAS2 antibody (Clone EM-50) (ABIN5633276) specifically detects R-RAS2 in ICFC.
The antibody is reactive with 人 samples.
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产品编号 ABIN5633276
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for R-RAS2 抗体 (PE) (ABIN5633276)
抗原
R-RAS2
适用
人
宿主
小鼠
克隆类型
单克隆
标记
PE
应用范围
Intracellular Flow Cytometry (ICFC)
克隆位点
EM-50
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原理
- Anti-R-RAS2 PE
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交叉反应 （详细）
- Human
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产品特性
- The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human TC21
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亚型
- IgG1, kappa
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anti-R-RAS2 antibody
适用: 人 ELISA, FACS, ICC, WB 宿主: 小鼠 Monoclonal EM-50 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze,Protect from prolonged exposure to light
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- R-RAS2
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背景
- RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2
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基因ID
- 22800
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UniProt
- P62070
抗原
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