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R-RAS2 抗体 (PE)

This anti-R-RAS2 antibody is a 小鼠 单克隆 antibody detecting R-RAS2 in ICFC. Suitable for 人.
产品编号 ABIN5633276
发货至: 中国
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Quick Overview for R-RAS2 抗体 (PE) (ABIN5633276)

抗原

R-RAS2

适用

宿主

  • 1
小鼠

克隆类型

  • 1
单克隆

标记

  • 1
PE

应用范围

  • 1
  • 1
  • 1
  • 1
Intracellular Flow Cytometry (ICFC)

克隆位点

EM-50
  • 原理

    Anti-R-RAS2 PE

    特异性

    The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human TC21

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    R-RAS2

    背景

    RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2

    基因ID

    22800

    UniProt

    P62070
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