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RRM2 抗体 (AA 1-110)

This anti-RRM2 antibody is a 小鼠 单克隆 antibody detecting RRM2 in WB, ELISA, IF, IP 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN562744
发货至: 中国

Quick Overview for RRM2 抗体 (AA 1-110) (ABIN562744)

抗原

See all RRM2 抗体
RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

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宿主

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小鼠

克隆类型

  • 44
  • 13
  • 1
单克隆

标记

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This RRM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1E1
  • 抗原表位

    • 15
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    AA 1-110

    原理

    Mouse monoclonal antibody raised against a partial recombinant RRM2.

    序列

    MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    RRM2 (NP_001025, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

    Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." in: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

    Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." in: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

    Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." in: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

    Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

  • 抗原

    RRM2 (Ribonucleotide Reductase M2 (RRM2))

    别名

    RRM2

    背景

    Full Gene Name: ribonucleotide reductase M2 polypeptide
    Synonyms: R2,RR2M

    基因ID

    6241

    NCBI登录号

    NM_001034

    途径

    Mitotic G1-G1/S Phases
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