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CNOT3 抗体 (AA 1-100)

This anti-CNOT3 antibody is a 小鼠 单克隆 antibody detecting CNOT3 in WB, ELISA 和 IF. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN562024
发货至: 中国

Quick Overview for CNOT3 抗体 (AA 1-100) (ABIN562024)

抗原

See all CNOT3 抗体
CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

适用

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宿主

  • 31
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小鼠

克隆类型

  • 31
  • 2
单克隆

标记

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This CNOT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

4B8
  • 抗原表位

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    AA 1-100

    原理

    Mouse monoclonal antibody raised against a partial recombinant CNOT3.

    序列

    MADKRKLQGE IDRCLKKVSE GVEQFEDIWQ KLHNAANANQ KEKYEADLKK EIKKLQRLRD QIKTWVASNE IKDKRQLIDN RKLIETQMER FKVVERETKT

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    CNOT3 (NP_055331, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Inoue, Morita, Hijikata, Fukuda-Yuzawa, Adachi, Isono, Ikawa, Kawamoto, Koseki, Natsume, Fukao, Ohara, Yamamoto, Kurosaki: "CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability." in: The Journal of experimental medicine, Vol. 212, Issue 9, pp. 1465-79, (2015) (PubMed).

    Kamon, Katano, Hiraki-Kamon, Hishida, Nakachi, Mizuno, Okazaki, Suzuki, Hirasaki, Ueda, Nishimoto, Kato, Okuda: "Identification of Ccr4-not complex components as regulators of transition from partial to genuine induced pluripotent stem cells." in: Stem cells and development, Vol. 23, Issue 18, pp. 2170-9, (2014) (PubMed).

    Doidge, Mittal, Aslam, Winkler: "The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex." in: PLoS ONE, Vol. 7, Issue 12, pp. e51331, (2012) (PubMed).

    Aslam, Mittal, Koch, Andrau, Winkler: "The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation." in: Molecular biology of the cell, Vol. 20, Issue 17, pp. 3840-50, (2009) (PubMed).

  • 抗原

    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

    别名

    CNOT3

    背景

    Full Gene Name: CCR4-NOT transcription complex, subunit 3
    Synonyms: KIAA0691,LENG2,NOT3,NOT3H

    基因ID

    4849

    NCBI登录号

    NM_014516

    途径

    Stem Cell Maintenance
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