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LETM1 抗体 (AA 601-708)

LETM1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
产品编号 ABIN561659
发货至: 中国
  • 抗原 See all LETM1 抗体
    LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
    抗原表位
    • 15
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-708
    适用
    • 54
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 2
    小鼠
    克隆类型
    • 54
    单克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LETM1 antibody is un-conjugated
    应用范围
    • 50
    • 24
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant LETM1.
    序列
    ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVA
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    6F7
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Chen, Yang, Liu, Piao, Zhang, Lin, Li: "High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma." in: BioMed research international, Vol. 2014, pp. 850316, (2014) (PubMed).

    Doonan, Chandramoorthy, Hoffman, Zhang, Cárdenas, Shanmughapriya, Rajan, Vallem, Chen, Foskett, Cheung, Houser, Madesh: "LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4936-49, (2014) (PubMed).

    Shin, Chung, Kang, Jiang, Yu, Han, Chae, Moon, Jang, Cho: "Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice." in: Cancer gene therapy, Vol. 20, Issue 3, pp. 186-94, (2013) (PubMed).

    Piao, Li, Kim, Sohn, Yang, Park, Byun, Won, Hong, Hur, Seok, Shong, Sack, Brazil, Hemmings, Park: "Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis." in: Cellular signalling, Vol. 21, Issue 5, pp. 767-77, (2009) (PubMed).

    Piao, Li, Kim, Byun, Huang, Hwang, Yang, Park, Won, Hong, Hur, Seok, Shong, Cho, Brazil, Hemmings, Park: "Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death." in: Cancer research, Vol. 69, Issue 8, pp. 3397-404, (2009) (PubMed).

    Dimmer, Navoni, Casarin, Trevisson, Endele, Winterpacht, Salviati, Scorrano: "LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability." in: Human molecular genetics, Vol. 17, Issue 2, pp. 201-14, (2008) (PubMed).

  • 抗原
    LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))
    别名
    LETM1 (LETM1 产品)
    背景
    Full Gene Name: leucine zipper-EF-hand containing transmembrane protein 1
    Synonyms:
    基因ID
    3954
    NCBI登录号
    NM_012318
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