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LETM1 抗体 (AA 601-708)

This anti-LETM1 antibody is a 小鼠 单克隆 antibody detecting LETM1 in WB, ELISA, IF, IP 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN561659
发货至: 中国

Quick Overview for LETM1 抗体 (AA 601-708) (ABIN561659)

抗原

See all LETM1 抗体
LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

适用

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宿主

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小鼠

克隆类型

  • 53
单克隆

标记

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This LETM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

6F7
  • 抗原表位

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    AA 601-708

    原理

    Mouse monoclonal antibody raised against a partial recombinant LETM1.

    序列

    ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVA

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    LETM1 (NP_036450, 601 a.a. ~ 708 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Chen, Yang, Liu, Piao, Zhang, Lin, Li: "High expression of leucine zipper-EF-hand containing transmembrane protein 1 predicts poor prognosis in head and neck squamous cell carcinoma." in: BioMed research international, Vol. 2014, pp. 850316, (2014) (PubMed).

    Doonan, Chandramoorthy, Hoffman, Zhang, Cárdenas, Shanmughapriya, Rajan, Vallem, Chen, Foskett, Cheung, Houser, Madesh: "LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4936-49, (2014) (PubMed).

    Shin, Chung, Kang, Jiang, Yu, Han, Chae, Moon, Jang, Cho: "Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice." in: Cancer gene therapy, Vol. 20, Issue 3, pp. 186-94, (2013) (PubMed).

    Piao, Li, Kim, Sohn, Yang, Park, Byun, Won, Hong, Hur, Seok, Shong, Sack, Brazil, Hemmings, Park: "Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis." in: Cellular signalling, Vol. 21, Issue 5, pp. 767-77, (2009) (PubMed).

    Piao, Li, Kim, Byun, Huang, Hwang, Yang, Park, Won, Hong, Hur, Seok, Shong, Cho, Brazil, Hemmings, Park: "Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death." in: Cancer research, Vol. 69, Issue 8, pp. 3397-404, (2009) (PubMed).

    Dimmer, Navoni, Casarin, Trevisson, Endele, Winterpacht, Salviati, Scorrano: "LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability." in: Human molecular genetics, Vol. 17, Issue 2, pp. 201-14, (2008) (PubMed).

  • 抗原

    LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

    别名

    LETM1

    背景

    Full Gene Name: leucine zipper-EF-hand containing transmembrane protein 1
    Synonyms:

    基因ID

    3954

    NCBI登录号

    NM_012318
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