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ATRX 抗体 (AA 2311-2492)

This anti-ATRX antibody is a 小鼠 单克隆 antibody detecting ATRX in ELISA. Suitable for 人.
产品编号 ABIN5611354
发货至: 中国

Quick Overview for ATRX 抗体 (AA 2311-2492) (ABIN5611354)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

  • 73
  • 17
  • 4
  • 3
  • 2
  • 2

宿主

  • 44
  • 31
  • 1
小鼠

克隆类型

  • 45
  • 31
单克隆

标记

  • 39
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATRX antibody is un-conjugated

应用范围

  • 30
  • 28
  • 21
  • 20
  • 12
  • 11
  • 11
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
ELISA

克隆位点

8B2H9
  • 抗原表位

    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2311-2492

    原理

    ATRX Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human ATRX (AA: 2311-2492) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    分子量

    282.5 kDa

    基因ID

    546
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