CD207 抗体 (AA 155-328)
Quick Overview for CD207 抗体 (AA 155-328) (ABIN5611331)
抗原
See all CD207 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 155-328
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原理
- CD207 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD207 (AA: 155-328) expressed in E. Coli.
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亚型
- IgG2b
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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别名
- CD207
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背景
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The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
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分子量
- 36.7 kDa
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UniProt
- Q9UJ71
抗原
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