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CCR7 抗体

This anti-CCR7 antibody is a 小鼠 单克隆 antibody detecting CCR7 in FACS, WB 和 ELISA. Suitable for 人.
产品编号 ABIN5611258
发货至: 中国

Quick Overview for CCR7 抗体 (ABIN5611258)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

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宿主

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小鼠

克隆类型

  • 72
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  • 1
单克隆

标记

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This CCR7 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA

克隆位点

4B7B8
  • 原理

    CD197 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD197 (AA: mix) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

    分子量

    42.9 kDa

    基因ID

    1236

    UniProt

    P32248

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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