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CCR7 抗体

CCR7 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 4B7B8 unconjugated
产品编号 ABIN5611258
发货至: 中国
  • 抗原 See all CCR7 抗体
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    适用
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    宿主
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    小鼠
    克隆类型
    • 68
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    单克隆
    标记
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    This CCR7 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), ELISA
    原理
    CD197 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CD197 (AA: mix) expressed in E. Coli.
    克隆位点
    4B7B8
    亚型
    IgG1
    Top Product
    Discover our top product CCR7 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    别名
    CD197 (CCR7 产品)
    背景
    The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
    分子量
    42.9 kDa
    基因ID
    1236
    UniProt
    P32248
    途径
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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