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CD16 抗体 (AA 17-208)

The 小鼠 单克隆 anti-CD16 antibody is suitable to detect CD16 in samples from 人. It has been validated for FACS 和 ELISA.
产品编号 ABIN5611218
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD16 抗体 (AA 17-208) (ABIN5611218)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

  • 186
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  • 1
单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA

克隆位点

2G10A9
  • 抗原表位

    • 8
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    • 1
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    AA 17-208

    原理

    CD16 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD16 (AA: 17-208) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CD16

    别名

    CD16

    背景

    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    29 kDa

    基因ID

    2214

    UniProt

    P08637

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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