GRIK2 抗体 (AA 45-226)
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Quick Overview for GRIK2 抗体 (AA 45-226) (ABIN5611208)
抗原
See all GRIK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 45-226
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原理
- GRIK2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human GRIK2 (AA: 45-226) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))
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别名
- GRIK2
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背景
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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
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分子量
- 102.5 kDa
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基因ID
- 2898
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途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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