Metabotropic Glutamate Receptor 1 抗体 (AA 387-486)
Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (AA 387-486) (ABIN5611175)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 387-486
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原理
- GRM1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human GRM1 (AA: 387-486) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- GRM1
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背景
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This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 132.4 kDa
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基因ID
- 2911
抗原
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