IGHM 抗体 (AA 310-452)
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- 抗原 See all IGHM products
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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抗原表位
- AA 310-452
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGHM antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), ELISA
- 原理
- IGHM Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human IGHM (AA: 310-452) expressed in E. Coli.
- 克隆位点
- 8B9D3
- 亚型
- IgG1
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anti-Immunoglobulin Heavy Constant mu (IGHM) antibody
IGHM 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal IGHM-3776R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB, StM, FACS, IF 宿主: 小鼠 Monoclonal IM373 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 45-178) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 1-489) antibodyIGHM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 兔 Monoclonal IGHM-3135R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rIM373 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal rIGHM-1623 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 103-131) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 391-440) antibodyIGHM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
- 别名
- IGHM (IGHM 产品)
- 背景
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Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD, MIM 1471770) on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma (summary by Janeway et al., 2005).
- 分子量
- 49.3 kDa
- UniProt
- P01871
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