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GRM7 抗体 (AA 454-590)

This anti-GRM7 antibody is a 小鼠 单克隆 antibody detecting GRM7 in ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5611161
发货至: 中国

Quick Overview for GRM7 抗体 (AA 454-590) (ABIN5611161)

抗原

See all GRM7 抗体
GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

适用

  • 42
  • 19
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  • 2
  • 2
  • 1
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宿主

  • 35
  • 10
  • 1
小鼠

克隆类型

  • 36
  • 10
单克隆

标记

  • 34
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GRM7 antibody is un-conjugated

应用范围

  • 33
  • 18
  • 11
  • 8
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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

7G8D3
  • 抗原表位

    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
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    • 1
    • 1
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    • 1
    • 1
    AA 454-590

    原理

    GRM7 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human GRM7 (AA: 454-590) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

    别名

    GRM7

    背景

    L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    102.3 kDa

    基因ID

    2917

    UniProt

    Q14831

    途径

    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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