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GRM2 抗体 (AA 414-558)

This anti-GRM2 antibody is a 小鼠 单克隆 antibody detecting GRM2 in ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5611158
发货至: 中国

Quick Overview for GRM2 抗体 (AA 414-558) (ABIN5611158)

抗原

See all GRM2 抗体
GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

适用

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  • 1
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宿主

  • 67
  • 5
  • 1
小鼠

克隆类型

  • 62
  • 11
单克隆

标记

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  • 5
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  • 2
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This GRM2 antibody is un-conjugated

应用范围

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  • 4
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ELISA, Flow Cytometry (FACS)

克隆位点

4A10B9
  • 抗原表位

    • 15
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    • 2
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    • 1
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    AA 414-558

    原理

    GRM2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human GRM2 (AA: 414-558) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

    别名

    GRM2

    背景

    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.

    分子量

    95.6 kDa

    基因ID

    2912

    UniProt

    Q14416

    途径

    cAMP Metabolic Process, Dicarboxylic Acid Transport
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