DNM2 抗体 (AA 520-744)
Quick Overview for DNM2 抗体 (AA 520-744) (ABIN5611153)
抗原
See all DNM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 520-744
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原理
- Dynamin-2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human Dynamin-2 (AA: 520-744) expressed in E. Coli.
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亚型
- IgG2a
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- DNM2 (Dynamin 2 (DNM2))
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别名
- Dynamin-2
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背景
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Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
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分子量
- 98 kDa
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基因ID
- 1785
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途径
- Toll-Like Receptors Cascades
抗原
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