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BCR 抗体 (AA 139-280)

Name: BCR 抗体 (AA 139-280)
Brand: antibodies-online
SKU: ABIN5611129
Availability: OutOfStock

BCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated

Western blot analysis using BCR mouse mAb against Jurkat (1), Hela (2), and Ramos (3) cell lysate. (BCR 抗体 (AA 139-280))

Black line: Control Antigen (100 ng),Purple line: Antigen (10 ng), Blue line: Antigen (50 ng), Red line:Antigen (100 ng) (BCR 抗体 (AA 139-280))

ELISA

Western blot analysis using BCR mAb against HEK293 (1) and BCR (AA: 139-280)-hIgGFc transfected HEK293 (2) cell lysate. (BCR 抗体 (AA 139-280))

Flow cytometric analysis of K562 cells using BCR mouse mAb (green) and negative control (red). (BCR 抗体 (AA 139-280))

FACS

Western blot analysis using BCR mAb against human BCR (AA: 139-280) recombinant protein. (BCR 抗体 (AA 139-280))

5 images

产品编号 ABIN5611129

发货至: 中国

Datasheet as PDF

抗原 See all BCR 抗体

BCR (Breakpoint Cluster Region (BCR))
抗原表位
28

15

7

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 139-280
适用
91

50

25

4

2

2

1

1

1

1
人
宿主
85

4

3
小鼠
Compatible Secondaries
克隆类型
88

4
单克隆
标记
54

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This BCR antibody is un-conjugated
应用范围
64

35

31

24

24

22

17

15

10

6

5

4

3

2

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

原理

BCR Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.

克隆位点

1E11G12

亚型

IgG1

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应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
抗原

BCR (Breakpoint Cluster Region (BCR))

别名

BCR (BCR 产品)

背景

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

分子量

142.8 kDa

基因ID

613

UniProt

P11274

途径

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling