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BCR 抗体 (AA 139-280)

This anti-BCR antibody is a 小鼠 单克隆 antibody detecting BCR in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN5611129
发货至: 中国

Quick Overview for BCR 抗体 (AA 139-280) (ABIN5611129)

抗原

See all BCR 抗体
BCR (Breakpoint Cluster Region (BCR))

适用

  • 98
  • 56
  • 26
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 94
  • 4
  • 3
小鼠

克隆类型

  • 97
  • 4
单克隆

标记

  • 61
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCR antibody is un-conjugated

应用范围

  • 72
  • 37
  • 33
  • 27
  • 26
  • 26
  • 19
  • 15
  • 14
  • 11
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

1E11G12
  • 抗原表位

    • 30
    • 16
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-280

    原理

    BCR Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    BCR (Breakpoint Cluster Region (BCR))

    别名

    BCR

    背景

    A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    142.8 kDa

    基因ID

    613

    UniProt

    P11274

    途径

    Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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