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GBA 抗体 (AA 146-235)

Cited in 5+ publications. This anti-GBA antibody is a 小鼠 单克隆 antibody detecting GBA in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN561009
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GBA 抗体 (AA 146-235) (ABIN561009)

抗原

See all GBA 抗体
GBA (Glucosidase, Beta, Acid (GBA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This GBA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2E2
  • 抗原表位

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    AA 146-235

    原理

    Mouse monoclonal antibody raised against a partial recombinant GBA.

    序列

    SYFSEEGIGY NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FSLPEEDTKL KIPLIHRALQ LAQRPVSLLA SPWTSPTWLK TNGAVNGKGS

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    GBA (NP_000148, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Murphy, Gysbers, Abbott, Tayebi, Kim, Sidransky, Cooper, Garner, Halliday: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." in: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).

    Bendikov-Bar, Rapaport, Larisch, Horowitz: "Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS." in: Orphanet journal of rare diseases, Vol. 9, pp. 86, (2014) (PubMed).

    Bendikov-Bar, Horowitz: "Gaucher disease paradigm: from ERAD to comorbidity." in: Human mutation, Vol. 33, Issue 10, pp. 1398-407, (2012) (PubMed).

    Bendikov-Bar, Ron, Filocamo, Horowitz: "Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant." in: Blood cells, molecules & diseases, Vol. 46, Issue 1, pp. 4-10, (2011) (PubMed).

    Campeau, Rafei, Boivin, Sun, Grabowski, Galipeau: "Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome." in: Blood, Vol. 114, Issue 15, pp. 3181-90, (2009) (PubMed).

  • 抗原

    GBA (Glucosidase, Beta, Acid (GBA))

    别名

    GBA

    背景

    Full Gene Name: glucosidase, beta, acid (includes glucosylceramidase)
    Synonyms: GBA1,GCB,GLUC

    基因ID

    2629

    NCBI登录号

    NM_000157

    途径

    Cellular Glucan Metabolic Process
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