GBA 抗体 (AA 146-235)
Quick Overview for GBA 抗体 (AA 146-235) (ABIN561009)
抗原
See all GBA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 146-235
-
原理
- Mouse monoclonal antibody raised against a partial recombinant GBA.
-
序列
- SYFSEEGIGY NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FSLPEEDTKL KIPLIHRALQ LAQRPVSLLA SPWTSPTWLK TNGAVNGKGS
-
交叉反应
- 人
-
产品特性
- Antibody Reactive Against Recombinant Protein.
-
免疫原
- GBA (NP_000148, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- In 1x PBS, pH 7.4
-
注意事项
- Aliquot to avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
-
: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." in: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).
: "Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS." in: Orphanet journal of rare diseases, Vol. 9, pp. 86, (2014) (PubMed).
: "Gaucher disease paradigm: from ERAD to comorbidity." in: Human mutation, Vol. 33, Issue 10, pp. 1398-407, (2012) (PubMed).
: "Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant." in: Blood cells, molecules & diseases, Vol. 46, Issue 1, pp. 4-10, (2011) (PubMed).
: "Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome." in: Blood, Vol. 114, Issue 15, pp. 3181-90, (2009) (PubMed).
-
: "Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease." in: Brain : a journal of neurology, Vol. 137, Issue Pt 3, pp. 834-48, (2014) (PubMed).
-
- GBA (Glucosidase, Beta, Acid (GBA))
-
别名
- GBA
-
背景
-
Full Gene Name: glucosidase, beta, acid (includes glucosylceramidase)
Synonyms: GBA1,GCB,GLUC -
基因ID
- 2629
-
NCBI登录号
- NM_000157
-
途径
- Cellular Glucan Metabolic Process
抗原
-