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Filamin A 抗体 (AA 1-838)

Name: Filamin A 抗体 (AA 1-838)
SKU: ABIN560922
Availability: OutOfStock

This anti-Filamin A antibody is a 小鼠单克隆 antibody detecting Filamin A in WB, ELISA, IHC (p) 和 PLA. Suitable for 人. This Primary Antibody has been cited in 8+ publications.

FLNA monoclonal antibody (M01), clone 4E10-1B2 Western Blot analysis of FLNA expression in HL-60 . (Filamin A 抗体 (AA 1-838))

Immunoperoxidase of monoclonal antibody to FLNA on formalin-fixed paraffin-embedded human lymphoma tissue. (Filamin A 抗体 (AA 1-838))

ISt

Detection limit for recombinant GST tagged FLNA is approximately 0. (Filamin A 抗体 (AA 1-838))

ELISA

Proximity Ligation Analysis of protein-protein interactions between GP1BA and FLNA. (Filamin A 抗体 (AA 1-838))

PLA

Western Blot detection against Immunogen (117. (Filamin A 抗体 (AA 1-838))

5 images

(8 references)

产品编号 ABIN560922

发货至: 中国

Quick Overview for Filamin A 抗体 (AA 1-838) (ABIN560922)

抗原

See all Filamin A (FLNA) 抗体

Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Filamin A antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

克隆位点

4E10-1B2

Discover our top product FLNA Primary Antibody

抗原表位
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AA 1-838

原理

Mouse monoclonal antibody raised against a full length recombinant FLNA.

序列

MPSGKVAQPT ITDNKDGTVT VRYAPSEAGL HEMDIRYDNM HIPGSPLQFY VDYVNCGHVT AYGPGLTHGV VNKPATFTVN TKDAGEGGLS LAIEGPSKAE ISCTDNQDGT CSVSYLPVLP GDYSILVKYN EQHVPGSPFT ARVTGDDSMR MSHLKVGSAA DIPINISETD LSLLTATVVP PSGREEPCLL KRLRNGHVGI SFVPKETGEH LVHVKKNGQH VASSPIPVVI SQSEIGDASR VRVSGQGLHE GHTFEPAEFI IDTRDAGYGG LSLSIEGPSK VDINTEDLED GTCRVTYCPT EPGNYIINIK FADQHVPGSP FSVKVTGEGR VKESITRRRR APSVANVGSH CDLSLKIPEI SIQDMTAQVT SPSGKTHEAE IVEGENHTYC IRFVPAEMGT HTVSVKYKGQ HVPGSPFQFT VGPLGEGGAH KVRAGGPGLE RAEAGVPAEF SIWTREAGAG GLAIAVEGPS KAEISFEDRK DGSCGVAYVV QEPGDYEVSV KFNEEHIPDS PFVVPVASPS GDARRLTVSS LQESGLKVNQ PASFAVSLNG AKGAIDAKVH SPSGALEECY VTEIDQDKYA VRFIPRENGV YLIDVKFNGT HIPGSPFKIR VGEPGHGGDP GLVSAYGAGL EGGVTGNPAE FVVNTSNAGA GALSVTIDGP SKVKMDCQEC PEGYRVTYTP MAPGSYLISI KYGGPYHIGG SPFKAKVTGP RLVSNHSLHE TSSVFVDSLT KATCAPQHGA PGPGPADASK VVAKGLGLSK AYVGQKSSFT VDCSKAGNNM LLVGVHGPRT PCEEILVKHV GSRLYSVSYL LKDKGEYTLV VKWGDEHIPG SPYRVVVP

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

FLNA (AAH14654, 1 a.a. ~ 838 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

亚型

IgG1
anti-Filamin A, alpha (FLNA) (AA 2-274) antibody
FLNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) antibody
FLNA 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) (pSer2152) antibody
FLNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) (AA 1819-2068) antibody
FLNA 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) (AA 1234-1462) antibody
FLNA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) antibody
FLNA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Filamin A, alpha (FLNA) (AA 1-838) antibody
FLNA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B6-1D10 unconjugated

anti-Filamin A, alpha (FLNA) (AA 1025-1054) antibody
FLNA 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB14246 unconjugated

anti-Filamin A, alpha (FLNA) (AA 1-839) antibody
FLNA 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated

anti-Filamin A, alpha (FLNA) (AA 1-839) antibody
FLNA 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 4E10-1B2 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Mingione, Verdelli, Ferrero, Vaira, Guarnieri, Scillitani, Vicentini, Balza, Beretta, Terranegra, Vezzoli, Soldati, Corbetta: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).

Parrini, Mei, Pisanti, Catarzi, Pucatti, Bianchini, Mascalchi, Bertini, Morrone, Cavaliere, Guerrini: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).

Bézie, Picarda, Tesson, Renaudin, Durand, Ménoret, Mérieau, Chiffoleau, Guillonneau, Caron, Anegon: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).

Peverelli, Giardino, Treppiedi, Vitali, Cambiaghi, Locatelli, Lasio, Spada, Lania, Mantovani: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).

Oegema, Hulst, Theuns-Valks, van Unen, Schot, Mancini, Schipper, de Wit, Sibbles, de Coo, Nanninga, Hofstra, Halley, Brooks: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).

Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

Peverelli, Mantovani, Vitali, Elli, Olgiati, Ferrero, Laws, Della Mina, Villa, Beck-Peccoz, Spada, Lania: "Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. 967-77, (2012) (PubMed).

Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: "Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ..." in: Nature genetics, Vol. 42, Issue 7, pp. 619-25, (2010) (PubMed).
抗原

Filamin A (FLNA) (Filamin A, alpha (FLNA))

别名

FLNA

背景

Full Gene Name: filamin A, alpha (actin binding protein 280)
Synonyms: ABP-280,ABPX,DKFZp434P031,FLN,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2

基因ID

2316

途径

TCR Signaling, Maintenance of Protein Location