-
- 抗原
- RbAp46/48
- 适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- 非结合性
- 应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 纯化方法
- Ascites fluid from mouse containing 0.05% azide
- 免疫原
- Monoclonal antibody raised in mouse against the full length human RbAp48 protein (Retinoblastoma-binding protein p48) fused to GST. The antibody recognizes both RbAp48 and RbAp46
- 克隆位点
- 6D1
- 亚型
- IgG2b
-
anti-RbAp46/48 antibody
适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascites fluid with 0.05 % sodium azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- RbAp46/48
- 别名
- RbAp 46/48
- 背景
-
Synonyms: Histone-binding protein RBBP4, RBBP4, p48, RBBP-4, RBAP48
Background: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
- 基因ID
- 5928
- UniProt
- Q09028
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