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Endothelin 1 抗体 (AA 113-212)

Cited in 3+ publications. This 小鼠 单克隆 anti-Endothelin 1 antibody (Clone 3D6) specifically detects Endothelin 1 in WB, IP 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN560688
发货至: 中国
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Quick Overview for Endothelin 1 抗体 (AA 113-212) (ABIN560688)

抗原

See all Endothelin 1 (EDN1) 抗体
Endothelin 1 (EDN1)

适用

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宿主

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小鼠

克隆类型

  • 93
  • 36
单克隆

标记

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This Endothelin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), ELISA

克隆位点

3D6
  • 抗原表位

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    AA 113-212

    原理

    Mouse monoclonal antibody raised against a partial recombinant EDN1.

    序列

    SQKDKKCWNF CQAGKELRAE DIMEKDWNNH KKGKDCSKLG KKCIYQQLVR GRKIRRSSEE HLRQTRSETM RNSVKSSFHD PKLKGNPSRE RYVTHNRAHW

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    EDN1 (AAH09720, 113 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Marion, Dieudonné, Patiño-Garcia, Lecanda, Marie, Modrowski: "Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 130, Issue 11, pp. 2514-25, (2012) (PubMed).

    Schildroth, Rettig-Zimmermann, Kalk, Steege, Fähling, Sendeski, Paliege, Lai, Bachmann, Persson, Hocher, Patzak: "Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 26, Issue 3, pp. 779-89, (2011) (PubMed).

    Ghoul, Serova, Astorgues-Xerri, Bieche, Bousquet, Varna, Vidaud, Phillips, Weill, Benhadji, Lokiec, Cvitkovic, Faivre, Raymond: "Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells." in: Cancer research, Vol. 69, Issue 10, pp. 4260-9, (2009) (PubMed).

  • 抗原

    Endothelin 1 (EDN1)

    别名

    EDN1

    背景

    Full Gene Name: endothelin 1
    Synonyms: ET1,HDLCQ7

    基因ID

    1906

    途径

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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