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CTH 抗体 (AA 1-405)

There are 5+ publications for this product available. The 小鼠 单克隆 anti-CTH antibody is suitable to detect CTH in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN560522
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CTH 抗体 (AA 1-405) (ABIN560522)

抗原

See all CTH 抗体
CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

适用

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宿主

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小鼠

克隆类型

  • 54
  • 25
单克隆

标记

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This CTH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

2E12-1C10
  • 抗原表位

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    AA 1-405

    原理

    Mouse monoclonal antibody raised against a full length recombinant CTH.

    序列

    MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

    Dickhout, Carlisle, Jerome, Mohammed-Ali, Jiang, Yang, Mani, Garg, Banerjee, Kaufman, Maclean, Wang, Austin: "Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism." in: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7603-14, (2012) (PubMed).

    Maclean, Sikora, Kožich, Jiang, Greiner, Kraus, Krijt, Overdier, Collard, Brodsky, Meltesen, Crnic, Allen, Stabler, Elleder, Rozen, Patterson, Kraus: "A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment." in: Molecular genetics and metabolism, Vol. 101, Issue 2-3, pp. 153-62, (2010) (PubMed).

    dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: "Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4513-8, (2009) (PubMed).

    Zhang, Jiang, Fang, Yan, Song, Gupta, Schafer, Durante, Kruger, Yang, Wang: "Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice." in: Circulation, Vol. 120, Issue 19, pp. 1893-902, (2009) (PubMed).

  • 抗原

    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

    别名

    CTH

    背景

    Full Gene Name: cystathionase (cystathionine gamma-lyase)
    Synonyms: MGC9471

    基因ID

    1491

    途径

    ER-Nucleus Signaling, Warburg Effect
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