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CRX 抗体 (AA 1-95)

Cited in 10+ publications. This 小鼠 单克隆 anti-CRX antibody (Clone 4G11) specifically detects CRX in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN560473
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CRX 抗体 (AA 1-95) (ABIN560473)

抗原

See all CRX 抗体
CRX (Cone-Rod Homeobox (CRX))

适用

  • 36
  • 24
  • 23

宿主

  • 43
  • 6
  • 1
  • 1
小鼠

克隆类型

  • 36
  • 15
单克隆

标记

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  • 2
  • 2
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  • 1
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This CRX antibody is un-conjugated

应用范围

  • 27
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  • 10
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  • 1
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Western Blotting (WB), ELISA

克隆位点

4G11
  • 抗原表位

    • 15
    • 4
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    • 1
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    AA 1-95

    原理

    Mouse monoclonal antibody raised against a partial recombinant CRX.

    序列

    MMAYMNPGPH YSVNALALSG PSVDLMHQAV PYPSAPRKQR RERTTFTRSQ LEELEALFAK TQYPDVYARE EVALKINLPE SRVQVWFKNR RAKCR

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    CRX (NP_000545, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Khan, Walters, Li, Thomas, Miller, Zhang, Sciallis, Liu, Dlouhy, Fort, Archer, Demirci, Dou, Rao: "Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 11, pp. 1278-90, (2015) (PubMed).

    Reichman, Goureau: "Production of Retinal Cells from Confluent Human iPS Cells." in: Methods in molecular biology (Clifton, N.J.), Vol. 1357, pp. 339-51, (2015) (PubMed).

    Tran, Zhang, Zhang, Huecker, Hennig, Chen: "Mechanistically distinct mouse models for CRX-associated retinopathy." in: PLoS genetics, Vol. 10, Issue 2, pp. e1004111, (2014) (PubMed).

    Jayaram, Jones, Eastlake, Cottrill, Becker, Wiseman, Khaw, Limb: "Transplantation of photoreceptors derived from human Muller glia restore rod function in the P23H rat." in: Stem cells translational medicine, Vol. 3, Issue 3, pp. 323-33, (2014) (PubMed).

    Reichman, Terray, Slembrouck, Nanteau, Orieux, Habeler, Nandrot, Sahel, Monville, Goureau: "From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 23, pp. 8518-23, (2014) (PubMed).

    Xie, Zhang, Hashimoto, Tien, Chen, Ge, Yang: "Differentiation of retinal ganglion cells and photoreceptor precursors from mouse induced pluripotent stem cells carrying an Atoh7/Math5 lineage reporter." in: PLoS ONE, Vol. 9, Issue 11, pp. e112175, (2014) (PubMed).

    Carr, Vugler, Yu, Semo, Coffey, Moss, Greenwood: "The expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide." in: Molecular vision, Vol. 17, pp. 1701-15, (2011) (PubMed).

    Sakagami, Gan, Yang: "Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 21, pp. 6932-44, (2009) (PubMed).

    Esumi, Kachi, Hackler, Masuda, Yang, Campochiaro, Zack: "BEST1 expression in the retinal pigment epithelium is modulated by OTX family members." in: Human molecular genetics, Vol. 18, Issue 1, pp. 128-41, (2008) (PubMed).

    Peng, Chen: "Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation." in: Human molecular genetics, Vol. 16, Issue 20, pp. 2433-52, (2007) (PubMed).

  • 抗原

    CRX (Cone-Rod Homeobox (CRX))

    别名

    CRX

    背景

    Full Gene Name: cone-rod homeobox
    Synonyms: CORD2,CRD,LCA7,OTX3

    基因ID

    1406

    NCBI登录号

    NM_000554
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