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RORC 抗体 (pSer203)

Name: RORC 抗体 (pSer203)
Brand: antibodies-online
SKU: ABIN5596977
Availability: OutOfStock

RORC 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western Blot of Rabbit anti-receptor ROR gamma pS203 antibody. (RORC 抗体 (pSer203))

1 image

产品编号 ABIN5596977

发货至: 中国

Datasheet as PDF

抗原 See all RORC 抗体

RORC (RAR-Related Orphan Receptor C (RORC))
抗原表位
16

7

7

6

6

6

5

5

4

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer203
适用
97

53

23

9

8

8

6

6

6

4

3

2

1

1

1

1

1

1

1

1
小鼠
宿主
79

17

2

1

1
兔
Compatible Secondaries
克隆类型
82

18
多克隆
标记
52

7

5

5

5

5

2

2

2

2

2

2

2

2

2

1

1

1
This RORC antibody is un-conjugated
应用范围
79

36

24

24

15

13

11

4

4

3

2

2

1

1

1
Western Blotting (WB), ELISA

交叉反应（详细）

A BLAST analysis was used to suggest reactivity with this protein with pongo abelii based on 100% homology for the immunogen sequence.

纯化方法

Anti-nuclear receptor ROR gamma pS203 is directed against mouse receptor ROR gamma phosphorylated at the serine 203 position. This product is an affinity purified antibody produced by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide to remove any unwanted reactivities.

免疫原

Immunogen: Affinity purified Anti-receptor ROR gamma pS203 antibody was prepared from whole rabbit serum produced by repeated immunizations with an internal synthetic peptide phosphorylated at the serine 203 position of mouse receptor ROR gamma protein.
Immunogen Type: Peptide

亚型

IgG

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应用备注

Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 61 kDa in size corresponding to receptor ROR gamma by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 5 μg/mL

限制

仅限研究用
状态

Liquid

浓度

1.05 mg/mL

缓冲液

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

有效期

12 months
抗原

RORC (RAR-Related Orphan Receptor C (RORC))

别名

Nuclear receptor ROR gamma (RORC 产品)

别名

NR1F3 antibody, RORG antibody, RZR-GAMMA antibody, RZRG antibody, TOR antibody, Nr1f3 antibody, RORgamma antibody, Thor antibody, RAR related orphan receptor C antibody, RAR-related orphan receptor C antibody, RAR-related orphan receptor gamma antibody, RORC antibody, Rorc antibody

背景

Synonyms: Nr1f3, Rorg, Thor, RAR-related orphan receptor C, Nuclear receptor RZR-gamma, Thymus orphan receptor
Background: Anti-Nuclear receptor ROR gamma pS203 was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Nuclear receptor ROR gamma pS203 antibody detects mouse receptor ROR gamma phosphorylated at the serine 203 position. RAR-related orphan receptor gamma (ROR-γ) is a member of the nuclear receptor family of transcription factors. ROR-γ is a key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. ROR-γ regulates the circadian expression of clock genes such as CRY1, ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner. It is also involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism and is a negative regulator of adipocyte differentiation. It controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity. Isoform 2, ROR-γt is essential for lymphoid organogenesis, in particular lymph nodes and Peyer's patches. ROR-γt also plays an important regulatory role in thymopoiesis, and in inhibiting apoptosis of undifferentiated T cells. Anti-nuclear receptor ROR gamma pS203 is ideal for researcher's interested in autoimmune diseases such as psoriasis and rheumatoid arthritis, circadian rhythms, and immune system disorders.
Gene Name: Rorc

基因ID

19885

NCBI登录号

NP_001280663

UniProt

P51450

途径

Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway