SETDB2 抗体
Quick Overview for SETDB2 抗体 (ABIN5596921)
抗原
See all SETDB2 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-n99
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Supplier
- Rockland
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原理
- Setdb2 Antibody
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交叉反应 (详细)
- This Protein A purified antibody is directed against mouse Setdb2.
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产品特性
- Synonyms: rabbit anti-Setdb2, Histone-lysine N-methyltransferase SETDB2, SET domain bifurcated 2, Setdb 2 antibody, Gm293
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纯化方法
- The product was purified from monospecific antiserum by Protein A affinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Setdb2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a full length protein corresponding to mouse Setdb2.
Immunogen Type: Recombinant Protein
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亚型
- IgG
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应用备注
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Application Note: Anti-Setdb2 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80.6 kDa in size corresponding to Setdb2 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:10,000 - 1:100,000
ELISA Dilution: 1:2,500 - 1:10,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.98 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- SETDB2 (SET Domain, Bifurcated 2 (SETDB2))
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别名
- Setdb2
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背景
- Background: Setdb2 is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI). Setdb2 and the neighboring gene Phf11 were linked to familial atopy/ asthma and are in a "critical region" commonly deleted in CLL. Setdb2 is a candidate histone methyltransferase as a member of the Su(var) 3-9 family of SET domain-containing enzymes. Other predicted domains in Setdb2 include a methylcytosine binding domain and a large bifurcation domain interrupting the putative histone methyltransferase (SET) domain whose function is unknown. Anti-Setdb2 antibody is ideal for researchers interested in Cancer Research and Epigenetics Research.
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UniProt
- Q8C267
抗原
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