ORM1 抗体 (HRP)
Quick Overview for ORM1 抗体 (HRP) (ABIN5596920)
抗原
See all ORM1 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-403-046-0100
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Supplier
- Rockland
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原理
- Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugated
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交叉反应 (详细)
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified a-1-Acid Glycoprotein [Human Plasma].
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产品特性
- Synonyms: rabbit anti-Alpha-1-Acid Glycoprotein Antibody Peroxidase Conjugation, HRP conjugated rabbit anti-Alpha-1-Acid Glycoprotein 1 Antibody, AGP1, AGP 1, OMD 1, OMD1, Orosomucoid-1
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纯化方法
- Anti-Alpha-1-Acid Glycoprotein Antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
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免疫原
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Immunogen: a-1-Acid Glycoprotein [Human Plasma]
Immunogen Type: Native Protein
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亚型
- IgG
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应用备注
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Immunohistochemistry Dilution: 1:500 - 1:2,500
Application Note: Anti-Alpha-1-Acid Glycoprotein peroxidase Antibody has been tested by ELISA and dot blot and is suitable for Western Blot and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:100 - 1:500
ELISA Dilution: 1:1500
IF Microscopy Dilution: 1:50 - 1:250
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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浓度
- 1 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative: 0.01 % (w/v) Gentamicin Sulfate. Do NOT add Sodium Azide! -
储存液
- Gentamicin sulfate
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注意事项
- This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- ORM1 (Orosomucoid 1 (ORM1))
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别名
- ORM1
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背景
- Background: Alpha-1-Acid Glycoprotein Antibody detects alpha-1-acid glycoprotein (AGP or AAG. ) Alpha-1-acid glycoprotein is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3 % plasma protein).[1] Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV. The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels, if anything, there is a small increase in α1 acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal. Anti-Alpha-1-Acid Glycoprotein Antibody is ideal for investigators involved in infectious disease and cell cycle protein research.
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基因ID
- 5004
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NCBI登录号
- NP_000598
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UniProt
- P02763
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途径
- Response to Growth Hormone Stimulus
抗原
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