Caveolin-1 抗体 (N-Term)
Quick Overview for Caveolin-1 抗体 (N-Term) (ABIN5596911)
抗原
See all Caveolin-1 (CAV1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-j63
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Supplier
- Rockland
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原理
- Caveolin-1 Antibody
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交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with lemur, sheep, bat, rat, rabbit, pig, and primate based on 100 % sequence homology.
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产品特性
- Synonyms: rabbit anti-Caveolin-1 Antibody, CAV1, CAV, CAV 1, rabbit anti-Caveolin 1 Antibody
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纯化方法
- Anti-Caveolin 1 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-Caveolin 1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the N-terminus of human Caveolin-1 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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应用备注
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Application Note: Anti-Caveolin1 antibody has been tested in WB and is useful for ELISA and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~21 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.78 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 30 % Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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别名
- CAV1
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背景
- Background: Caveolin 1 is a ubiquitous protein found within the membranes of caveolea, theoretically acting as a scaffolding protein. Direct interaction with G-protein alpha subunits allows regulation of their activity. A regulatory protein, it is involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation, and is also a factor in the regulation of CTNNB1-mediated signaling through the Wnt pathway. Expressed in the muscle and lung tissues predominantly, defects in CAV1 is the cause of congenital generalized lipodystrophy type 3, or autosomal recessive disorders such as adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset diabetes. Anti-Caveolin 1 antibody is ideal for researchers in Metabolism, Cancer, Signal Transduction, and Cardiovascular research.
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UniProt
- Q03135
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途径
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
抗原
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