Huntingtin 抗体 (pSer421)
Quick Overview for Huntingtin 抗体 (pSer421) (ABIN5596736)
抗原
See all Huntingtin (HTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer421
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Supplier Product No.
- 600-401-j79
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Supplier
- Rockland
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原理
- Huntington phospho S421 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with human based on 100 % sequence homology.
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产品特性
- Synonyms: rabbit anti-Huntington pS421 antibody, rabbit anti-Huntingtin pS421 antibody, HD protein, HTT, Huntington Disease Protein, Huntington disease, IT15, LOMARS
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纯化方法
- Anti-Huntingtin pS421 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of the S421 residue.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-Huntington pS421 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Huntington disease protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Huntingtin (HTT) (AA 81-190) antibody
HTT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 85-200) antibodyHTT 适用: 人, 大鼠, 小鼠, 兔, 猴, 马, 犬, 绵羊, Pig, Hamster, 豚鼠, 山羊, 驴, Cow, 小鸡, Cat, Avian WB, IF, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Huntingtin (HTT) (AA 782-920) antibodyHTT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 6F2 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) (AA 81-191) antibodyHTT 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Huntingtin (HTT) (AA 2703-2911) antibodyHTT 适用: 人, 兔 IHC, WB, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-Huntingtin (HTT) (AA 751-850) antibodyHTT 适用: 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-HTT antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~350 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.07 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Huntingtin (HTT)
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别名
- HTT
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背景
- Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (HTT) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntington antibody is ideal for investigators interested in Neuroscience research.
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基因ID
- 3064
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NCBI登录号
- NP_002102
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UniProt
- P42858
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途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
抗原
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