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Huntingtin 抗体 (pSer1181)

Name: Huntingtin 抗体 (pSer1181)
SKU: ABIN5596734
Availability: OutOfStock

Rockland 600-401-j80 HTT 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN5596734

Supplier Product No.: 600-401-j80

发货至: 中国

Datasheet as PDF

抗原 See all Huntingtin (HTT) 抗体

Huntingtin (HTT)
抗原表位
15

6

4

4

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
pSer1181
适用
57

44

37

6

3

2

2

1

1

1

1

1

1

1

1

1

1
人, 大鼠, 小鼠
宿主
52

22

2
兔
Compatible Secondaries
克隆类型
45

30
多克隆
标记
55

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Huntingtin antibody is un-conjugated
应用范围
40

33

27

14

14

13

13

9

7

4

4

2

1

1
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Supplier Product No.

600-401-j80

Supplier

Rockland

原理

Huntington phospho S1181 Antibody

交叉反应（详细）

A BLAST analysis was used to suggest cross-reactivity with human, mouse, and rat based on 100 % sequence homology.

产品特性

Synonyms: rabbit anti-Huntington pS1181 antibody, rabbit anti-Huntingtin pS1181 antibody, HD protein, HTT, Huntington Disease Protein, Huntington disease, IT15, LOMARS

纯化方法

Anti-Huntingtin pS1181 was affinity purified from monospecific antiserum by immunoaffinity chromatography and is directed against the phosphorylated form of the S1181 residue.

过滤

Sterile filtered

免疫原

Immunogen: Anti-Huntingtin pS1181 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Huntington disease protein.
Immunogen Type: Conjugated Peptide

亚型

IgG

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应用备注

Immunohistochemistry Dilution: User Optimized
Application Note: Anti-HTT antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~350 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000

限制

仅限研究用
状态

Liquid

浓度

1.04 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol with 1 mg/mL Bovine Serum Albumin (BSA)
Preservative: None

储存液

Without preservative

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
抗原

Huntingtin (HTT)

别名

HTT (HTT 产品)

背景

Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntington antibody is ideal for investigators interested in Neuroscience research.

基因ID

3064

NCBI登录号

NP_002102

UniProt

P42858

途径

PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport