HDAC4 抗体 (AA 150-200)
Quick Overview for HDAC4 抗体 (AA 150-200) (ABIN5596723)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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Supplier Product No.
- 600-401-j42
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Supplier
- Rockland
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原理
- HDAC4 (internal) Antibody
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交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with mouse based on 100 % sequence homology.
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产品特性
- Synonyms: rabbit anti-HDAC-4 antibody, HDAC4, HDAC 4, HD 4 antibody, histone deacetylase 4 antibody, Histone deacetylase-4, HD4 antibody
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纯化方法
- Anti-HDAC4 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: HDAC4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region surrounding 150-200aa of mouse HDAC4.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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应用备注
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Application Note: Anti-HDAC4 antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~140 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1: 10,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.26 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 30 % Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
- HDAC4
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背景
- Background: HDAC4 antibody belongs to class II of the histone deacetylase/acuc/apha family. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC4 represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. Anti-HDAC4 is ideal for investigators interested in Stem Cell , Cardiovascular , and Epigenetics and Nuclear Signaling research.
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基因ID
- 9759
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NCBI登录号
- NP_006028
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UniProt
- P56524
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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