FIL1h 抗体
Quick Overview for FIL1h 抗体 (ABIN5564285)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human IL-36beta.
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交叉反应
- 人
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无交叉反应
- 小鼠
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交叉反应 （详细）
- Does not cross-react with mouse IL-36beta and IL-36gamma.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human IL-36beta.
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亚型
- IgG1
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anti-Interleukin 1 eta (FIL1h) (AA 1-157) antibody
FIL1h 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Interleukin 1 eta (FIL1h) (C-Term) antibodyFIL1h 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 eta (FIL1h) (AA 1-157) antibodyFIL1h 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 1 eta (FIL1h) (AA 1-30), (N-Term) antibodyFIL1h 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22631 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- FIL1h (Interleukin 1 eta (FIL1h))
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别名
- IL-36beta
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背景
- IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
抗原
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