IL1F10 抗体
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北京 101111
Quick Overview for IL1F10 抗体 (ABIN5564279)
抗原
See all IL1F10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-IL-38, mAb (Nhat-1)
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特异性
- Recognizes human and mouse IL-38.
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产品特性
- Monoclonal Antibody. Recognizes human and mouse IL-38. Isotype: Mouse IgG2bkappa. Clone: Nhat-1. Applications: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human IL-38.
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亚型
- IgG2b kappa
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anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) antibody
IL1F10 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 2A2B3 unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 1-152) antibodyIL1F10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 65-114) antibodyIL1F10 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (Internal Region) antibodyIL1F10 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 1-152) antibodyIL1F10 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (AA 15-152) antibodyIL1F10 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 10 (Theta) (IL1F10) (C-Term) antibodyIL1F10 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
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别名
- IL-38
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背景
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Alternate Names/Synonyms: Interleukin-38, Interleukin-1 Family Member 10, IL-1F10
Product Description: IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
抗原
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