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Recombinant Netrin 1 抗体

This anti-Netrin 1 antibody is a Human 单克隆 antibody detecting Netrin 1 in ELISA 和 Func. Suitable for 人 和 小鼠.
产品编号 ABIN5564235
发货至: 中国

Quick Overview for Recombinant Netrin 1 抗体 (ABIN5564235)

抗原

See all Netrin 1 (NTN1) 抗体
Netrin 1 (NTN1)

抗体类型

Recombinant Antibody

适用

  • 50
  • 42
  • 35
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 63
  • 8
  • 4
  • 2
  • 1
  • 1
Human

克隆类型

  • 69
  • 10
单克隆

标记

  • 47
  • 7
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Netrin 1 antibody is un-conjugated

应用范围

  • 62
  • 33
  • 18
  • 18
  • 15
  • 13
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
ELISA, Functional Studies (Func)

克隆位点

2F5
  • 特异性

    Recognizes human and mouse Netrin-1.

    交叉反应

    人, 小鼠

    无交叉反应

    小鼠

    交叉反应 (详细)

    Does not recognize Netrin-4. Blocks human and mouse Netrin-1 activity on tumor cell lines in vitro and in vivo. Inhibits Netrin-1-enhanced infectivity of Hepatitis C Virus particles.

    纯度

    >95 % (SDS-PAGE)

    免疫原

    Recombinant human Netrin-1.

    亚型

    IgG2
  • 说明

    anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain.For negative control see Prod. No. AG-27B-0020PF.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 10 % glycerol.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    Netrin 1 (NTN1)

    别名

    Netrin-1

    背景

    Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.

    UniProt

    O95631

    途径

    Regulation of Cell Size
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