Recombinant Rab6-GTP (Gln72Leu-Mutant) 抗体 (Atto 488)
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北京 101111
Quick Overview for Recombinant Rab6-GTP (Gln72Leu-Mutant) 抗体 (Atto 488) (ABIN5564232)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Gln72Leu-Mutant
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原理
- anti-Rab6-GTP, mAb (rec.) (AA2) (ATTO488)
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特异性
- Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L. Does not detect Rab6•GDP.
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交叉反应 （详细）
- Does not detect Rab6•GDP.
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产品特性
- Recombinant Antibody. Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L. Does not detect Rab6•GDP. Species cross-reactivity: Drosophila, Human, Mouse. Clone: AA2. Isotype: Human IgG2lambda. Applications: ICC. Host: Purified from HEK 293 cell culture supernatant. Liquid. In PBS containing 0.02 % sodium azide. Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant Rab6AQ72L, a GTP-locked mutant of Rab6A in which Gln72 is replaced by Leu.
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亚型
- IgG2 lambda
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说明
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anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain. anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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+4°C
+4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
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有效期
- 12 months
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- Rab6-GTP
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背景
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Alternate Names/Synonyms: Ras-related protein Rab-6
Product Description: Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
抗原
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