BRP44 抗体
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北京 101111
Quick Overview for BRP44 抗体 (ABIN5564218)
抗原
See all BRP44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-MPC-2, mAb (JCM-1)
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特异性
- Recognizes endogenous human and mouse MPC-2.
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产品特性
- Monoclonal Antibody. Recognizes endogenous human and mouse MPC-2. Isotype: Mouse IgG2bkappa. Clone: JCM-1. Applications: IP, WB. Liquid. In PBS containing 25 % glycerol and 0.02 % sodium azide. Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.
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免疫原
- Peptide coupled to KLH.
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亚型
- IgG2b kappa
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anti-Brain Protein 44 (BRP44) (AA 1-40) antibody
BRP44 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Brain Protein 44 (BRP44) (AA 98-127), (C-Term) antibodyBRP44 适用: 人 WB 宿主: 兔 Polyclonal RB33985 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 25 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- BRP44 (Brain Protein 44 (BRP44))
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别名
- MPC-2
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背景
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Alternate Names/Synonyms: Mitochondrial Pyruvate Carrier 2, Brain Protein 44
Product Description: Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Two proteins, mitochondrial pyruvate carriers MPC-1 and MPC-2, form a heterooligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation-critical reactions in intermediary metabolism that are dysregulated in several common metabolic diseases.
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途径
- Warburg Effect
抗原
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