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SFMBT1 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-SFMBT1 antibody (ABIN5563984) specifically detects SFMBT1 in WB, IP, ChIP, IF 和 ChIP-seq. The antibody is reactive with 小鼠 samples.
产品编号 ABIN5563984
发货至: 中国
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Quick Overview for SFMBT1 抗体 (C-Term) (ABIN5563984)

抗原

See all SFMBT1 抗体
SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This SFMBT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)
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    C-Term

    原理

    SFMBT1 antibody (pAb)

    特异性

    Mouse

    纯化方法

    Affinity Purified

    免疫原

    This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1.

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2,500 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

  • 抗原

    SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

    别名

    SFMBT1

    背景

    SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

    分子量

    110 kDa

    NCBI登录号

    NP_062333
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