SFMBT1 抗体 (C-Term)
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Quick Overview for SFMBT1 抗体 (C-Term) (ABIN5563984)
抗原
See all SFMBT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SFMBT1 antibody (pAb)
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特异性
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1.
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2,500 dilution
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).
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- SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))
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别名
- SFMBT1
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背景
- SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.
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分子量
- 110 kDa
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NCBI登录号
- NP_062333
抗原
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