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Recombinant SMAD2 抗体 (N-Term)

The 兔 单克隆 anti-SMAD2 antibody (ABIN5557538) specifically detects SMAD2 in WB, IF, FACS, ICC, IHC (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN5557538
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant SMAD2 抗体 (N-Term) (ABIN5557538)

抗原

See all SMAD2 抗体
SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This SMAD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    N-Term

    原理

    Smad2 Recombinant Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Smad2 protein, around N-terminal 1-200aa.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

    别名

    Smad2

    背景

    Synonyms: JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, Mad-related protein 2, SMAD family member 2, SMAD 2, Smad2

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    基因ID

    4087

    UniProt

    Q15796

    途径

    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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