HDAC4 抗体
Quick Overview for HDAC4 抗体 (ABIN5557481)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Purified by Protein A.
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免疫原
 - Recombinant human HDAC4 protein, around C-terminal 100aa.
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亚型
 - IgG
 
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应用备注
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                        WB 1:1000-2000
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C
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有效期
 - 12 months
 
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
 - HDAC4
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背景
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.
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基因ID
 - 9759
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UniProt
 - P56524
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途径
 - Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
 
抗原
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