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EIF4E 抗体 (pSer209)

This 兔 单克隆 anti-EIF4E antibody (Clone 2B1) specifically detects EIF4E in WB, IHC (p) 和 IF (cc). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN5557447
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EIF4E 抗体 (pSer209) (ABIN5557447)

抗原

See all EIF4E 抗体
EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

适用

  • 145
  • 89
  • 77
  • 20
  • 5
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人, 大鼠, 小鼠

宿主

  • 130
  • 15
  • 2

克隆类型

  • 100
  • 47
单克隆

标记

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This EIF4E antibody is un-conjugated

应用范围

  • 126
  • 69
  • 51
  • 39
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  • 26
  • 26
  • 15
  • 7
  • 6
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

2B1
  • 抗原表位

    • 52
    • 15
    • 8
    • 7
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    • 4
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    pSer209

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated Synthesised phosphopeptide derived from human EIF4E around the phosphorylation site of Ser209: SG(p-S)TT

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

    别名

    eIF4E

    背景

    Synonyms: CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein

    Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

    基因ID

    1977

    UniProt

    P06730

    途径

    BCR Signaling
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