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ALAS1 抗体

The 兔 单克隆 anti-ALAS1 antibody (Clone 1G11) (ABIN5557346) specifically detects ALAS1 in WB 和 IF (cc). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN5557346
发货至: 中国
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Quick Overview for ALAS1 抗体 (ABIN5557346)

抗原

See all ALAS1 抗体
ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

适用

  • 62
  • 22
  • 21
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 60
  • 2

克隆类型

  • 40
  • 22
单克隆

标记

  • 22
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ALAS1 antibody is un-conjugated

应用范围

  • 41
  • 15
  • 13
  • 12
  • 10
  • 7
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

1G11
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Alas1 protein, around C-terminal 200aa.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

    别名

    Alas1

    背景

    Synonyms: 5-aminolevulinate synthase, nonspecific, mitochondrial, ALAS1, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, ALAS1, ALAS3, ALASH, OK/SW-cl.121

    Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

    基因ID

    211

    UniProt

    P13196

    途径

    Regulation of Lipid Metabolism by PPARalpha
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