DOC2A 抗体 (AA 652-749)
Quick Overview for DOC2A 抗体 (AA 652-749) (ABIN5542714)
抗原
See all DOC2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 652-749
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原理
- DOC2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.
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亚型
- IgG1
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anti-Double C2-Like Domains, alpha (DOC2A) (AA 1-400) antibody
DOC2A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 277-306) antibodyDOC2A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB32573 unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 233-246) antibodyVerified DOC2A 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 1-400) antibodyDOC2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Double C2-Like Domains, alpha (DOC2A) (AA 284-314), (Middle Region) antibodyDOC2A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- DOC2A (Double C2-Like Domains, alpha (DOC2A))
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别名
- DOC2
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背景
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This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 82.4 kDa
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UniProt
- P98082
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途径
- Synaptic Vesicle Exocytosis
抗原
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