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DOC2A 抗体 (AA 652-749)

This anti-DOC2A antibody is a 小鼠 单克隆 antibody detecting DOC2A in ELISA, FACS 和 ICC. Suitable for 人.
产品编号 ABIN5542714
发货至: 中国

Quick Overview for DOC2A 抗体 (AA 652-749) (ABIN5542714)

抗原

See all DOC2A 抗体
DOC2A (Double C2-Like Domains, alpha (DOC2A))

适用

  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 13
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 17
  • 2
单克隆

标记

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
This DOC2A antibody is un-conjugated

应用范围

  • 16
  • 12
  • 9
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ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

2H7C4
  • 抗原表位

    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-749

    原理

    DOC2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    DOC2A (Double C2-Like Domains, alpha (DOC2A))

    别名

    DOC2

    背景

    This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    82.4 kDa

    UniProt

    P98082

    途径

    Synaptic Vesicle Exocytosis
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