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DOC2A 抗体 (AA 652-749)

DOC2A 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2H7C4 unconjugated
产品编号 ABIN5542714
发货至: 中国
  • 抗原 See all DOC2A 抗体
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    抗原表位
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-749
    适用
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 13
    • 3
    • 2
    • 1
    小鼠
    克隆类型
    • 17
    • 2
    单克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOC2A antibody is un-conjugated
    应用范围
    • 16
    • 12
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    DOC2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.
    克隆位点
    2H7C4
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    别名
    DOC2 (DOC2A 产品)
    背景
    This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    82.4 kDa
    UniProt
    P98082
    途径
    Synaptic Vesicle Exocytosis
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