SEC31A 抗体 (AA 429-571)
Quick Overview for SEC31A 抗体 (AA 429-571) (ABIN5542690)
抗原
See all SEC31A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 429-571
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原理
- SEC31A Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SEC31A (SEC31 Homolog A (SEC31A))
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别名
- SEC31A
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背景
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The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 133 kDa
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基因ID
- 22872
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UniProt
- O94979
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途径
- ER-Nucleus Signaling
抗原
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